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Oklahoma State University

Dr. Maxwell, Lara

Dr. Lara Maxwell, DVM, PhD, DACVCP
Professor
Department of Physiological Sciences
College of Veterinary Medicine
264 McElroy Hall
Stillwater, OK 74078
405-744-8092
lk.maxwell@okstate.edu

 

Research Interests:

I work on disparate topics, ranging from anticancer to antiviral drugs. However, these diverse lines of inquiry do fit within the unifying theme of my research: improving patient outcomes through pharmacokinetic and pharmacodynamic modeling. At its simplest, pharmacodynamic data reveal the actions of a xenobiotic on a pharmacological target, such as a receptor or a pathogen. The field of pharmacokinetics is closely related to xenobiotic disposition, but provides a mathematical description of the time course of xenobiotic movement through the body. Pharmacokinetic and pharmacodynamic modeling are most powerful when combined, as their union increases the odds of successfully predicting the actions of a xenobiotic as a function of both concentration and time. I use classical compartmental or noncompartmental, physiologically based, and population pharmacokinetic modeling. I agree with the axiom that “the dose makes the poison”, so enjoy both pharmacological and toxicological applications of xenobiotic modeling.

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